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CLEFT PALATE IN COCKER SPANIELS
  There is a lot of controversy in the cocker world between experts as to if cleft palates in cockers is a genetic trait or if it is more connected to the environment where herbicides and pesticides are used.  There has been much documentation of both sides of this issue.
    This is only an example using a male for the demonstration of cleft palates, if they where inherited.
     If cleft palate was a simple dominant and came from the paternal grandfather it would, also, be present in the father to some degree and would be passed from one generation to the next generation directly and because it is a visible condition could be selected against simply by not breeding affected individuals.
     If cleft palate were a simple recessive and came from the paternal grandfather, the father would be a carrier and so would the dam and one of her parents, because a recessive has to be inherited from both parents to be expressed.  To eliminate this condition you would have to quit breeding all individuals that produced an affected puppy, the suspected grandparents, uncles, aunts, ECT. Of the litter mates statistically two out of the three of the unaffected would be carriers and you couldn't tell by looking so none should be used as breeders.
     If it were polygenic, it would be coming from both sides of the family in more or less random fashion and would produce affected individuals on a probably inconsistent basis.  The only animals that would produce consistently affected progeny would, also, be affected.  To eliminate this condition (hopefully) would be to quit breeding all of those animals that are related to an affected puppy and start over with a completely unaffected line.
     If it were sex linked (there are several modes of inheritance) and came from the paternal grandfather it would be carried on the Y chromosome and be passed on to every male he produced and would only affect males.  To eliminate it in this circumstance, quit using all of the males in this line.
     If it came from the maternal grandfather and skipped a generation, it would be inherited from the mother (the grandfather, also, being affected.) It would be carried on the X chromosome and only expressed in the presents of male hormone (testosterone) and would show up at puberty, so obviously this is not the case.
     If cleft palate were inherited from the maternal grandfather and carried as a simple recessive on the X chromosome, it would only affect females and come from both parents.  To eliminate this, you would treat it as any other simple recessive.  Quit using the animals as breeders!
The above is just a scenario for the inheritability for cleft palates.  Below is an opinion that has been developed over the years with research and hands on experience.
     I believe that the condition has more to do with the environment than being an inherited trait.  When one encounters the cleft palates in puppies, it can be traced back to insecticides, herbicides and other hazardous materials.
      All cocker breeders interested in improving the breed and eliminating detrimental genes, should have at least a fundamental understating of basic Mendels Law .
      I recommend going to your local library and asking the reference librarian to point you in the right direction.
 
There has been some breeder research on the use of Folic Acid as an aid in preventing cleft palates.

Dosage: 1.5mg Folic Acid daily from     1st day of mating until
 3 weeks after whelping. However if cleft palates are a real problem
increase dose to 2.5mg tablets daily for the first 3 weeks of pregnancy.
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This page was last modified on: Friday, 07-Jan-2011 18:16:24 EST.